Karl Schmieder M.S./M.F.A.

Three by Five by Eleven.2

Posted in 3x5, Influences, Observations, Writing by Karl S. on January 25, 2018

Here’s this week’s 3×5.

like to work in 90 minute blocks of time, often split in sprints of 2×45.

To help focus, I’ll use a timer app: Forest on my phone, Freedom, on my computer, and Insight for meditation.

Of these, I find Forest the most useful and fun. You’re growing a (virtual) tree while you focus. You can choose different species of trees and more unlock over time. My current favorite: stalks of bamboo.

My niece Violeta introduced me and I am forever grateful.

I’ve been a fan of Steve Blank and Bob Dorf’s The Startup Owner’s Manual for a long time. It’s a big book. It’s also full of practical insights (“Get out of the building…”). I’ve recently been referring to it since I’m launching a new business offering. It’s a book that breaks down the Lean Startup process.

Tim Ferriss’ Impossible Questions (email subscription required). There’s 17 of them. I’ve been thinking about these…

Product Market Fit

Posted in 3x5, Book Reviews, Marketing, messagingLAB, Observations, Writing by Karl S. on January 24, 2018

Figuring out product-market fit’s probably harder than this game. Photo by Michał Parzuchowski on Unsplash

To paraphrase, Lean Startup author Eric Reis,

“We can build any product. The question is: Will anyone buy it?”

True Story:

She is developing a new chip set. It’s revolutionary in its design and potential applications.

When I ask about customers, she answers, “We’re building a platform, like the app store.”

When I ask about validated customers, she answers, “It will be a hundred times cheaper. Than the competition. They’ll all buy it. Wouldn’t you?”

When I asks about product-market fit, she asks, “What is that?”

It means, I explain, you have a product that people want to buy.

She repeat her statement about cheaper cost assuring – not just driving – sales.

To me, that’s the end of the conversation.

I can’t help people who haven’t spoken to their potential customers.

Or, those that think they don’t have to.

I can’t draft messages in a void.

I can. Sure. 

But there’s no guarantee they’ll work and I won’t take the risk.

If we agree with Reis (and I do), we’re lucky we can build almost any product today. We also have more knowledge about building businesses.

What we don’t have is insights into customers.

Will they buy our product?

Or not?

The Lean Startup methodology forces you to get in front of your customers.

It helps ensure that you’re developing something the market wants. Before you create it.

Wouldn’t you rather know that up front?

Image from SeekingWisdom.io

Why You Need a Bio Strategy

Three by Five by Eleven.1

Posted in 3x5, biotechnology, book notes, Influences, interviews, Observations, Science Fiction, Writing by Karl S. on January 19, 2018

I’m starting a new weekly feature. Not to clutter your life –  you can opt out if you’d like – but to document and share the things that influence me during a week.

To keep myself focused and brief, I promise to only share what fits on one side of a 3×5 filecard.

Why?

The file card. The notecard. A small piece of lined paper. Blank white, or colored.

Three inches by five inches. They’re typically printed with eleven lines.

Highly useful. I consider them an essential tool for a writer.

Easy enough to carry anywhere, they’re old school. Like a pencil.  They can be anti-technology. Turn off your phone, your computer, and focus your effort on the little card in front of you.

I usually carry around a stack but if I’m pressed for time or room, I’ll fold a couple, put them in my pocket, grab a pencil or pen.

Here’s this week’s file card:

Christopher Payne takes pictures of General Pencil, in New Jersey.

Inside One of America’s Last Pencil Factories – A New York Times Magazine photo essay on General Pencil Company. “Pencils eschew digital jujitsu. They are pure analog, absolute presence. They help to rescue us from oblivion.”

Genemapper – This near-future novel follows a “leaf and flower color” designer as he solves the mysterious collapse of a crop he designed. Full of ideas, especially around from-scratch genetic design.

The Chaco Quarterly because “one must distinguish between Information, knowledge, and wisdom.” Wisdom distilled into 90 seconds because there’s not enough wisdom in the world.

That wraps this first issue. What do you think?

 

What I’m Reading

The Veteran in the Field, Winslow Homer

Happy New Year!

Over the holidays, I unsubscribed from dozens of newsletters. I was very critical in thinking through whether a newsletter belonged in my email box. Was it helping me stay informed? Was it inspiring? Or, was it wasting (virtual) space? Here are a few of the newsletters I subscribe to stay up to date on biotech, pharma and synthetic biology news.

Biotech Newsletters

Biotech Investment Newsletters

Synthetic Biology Newsletters

Future Science

NY Local Newsletters

Miscellaneous Newsletters

I subscribe to few general business, sales, and inspirational newsletters from the following superstars:

I also subscribe to Nuzzel and receive a daily summary of the articles my Twitter network is reading.

What are you reading? Are there biotech newsletters that I missed?

Have you subscribed to messagingLAB’s newsletter? Sign up here.

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2017: A Year Wraps and Good Riddance

Good Riddance 2017

It was a good year, but not without its challenges.

The TL;DR is:

  • mL grew more than 10 percent but is still down from its 2015 high.
  • I co-authored and published What’s Your Bio Strategy?
  • I moderated a panel at SynBioBeta SF17 and keynoted at Biofabricate 4 and enjoyed it.
  • I now live with myaesthenia gravis.
  • I started a novel that’s been in my head for more than ten years.
  • I took time off to travel from Boston to Montreal on a family cruise. I also spent some quality time in the Adirondacks.

My three words were bold, creative, authority and I kept those in mind all year long.

Macro Events

New York City and my microcosm in Brooklyn was depressed after the 2016 election. (For God’s sake, there was a planned victory party – at the intersection of President and Clinton streets just a few blocks from I live.)

The sense of the unknown and dread filled the air. I mean you could, you really could, feel it. And I don’t say that lightly.

I counseled friends to focus on ONE issue. I suggested focusing on what you could control. I knew trying to make sense of everything would be overwhelming. That’s proved true.

I promised myself I’d focus on science and education. I emailed and called my senators and representatives when a science or education issue came up.

As the year progressed, my focus became local.  I started participating in fights against charter schools. I started calling representatives, at the local and state level on sad state of the New York City subways. This was me being bold.

As we enter 2018, I’d like to do a better job helping those who are less fortunate. Especially, those who don’t understand or speak the language, nor how the system works. As a communicator, that is one of my most important jobs.

Karl’s Life Personal

2017 was a weird year.

One morning in April, I woke up seeing double. I went to the emergency room and spent a day and night undergoing a battery of tests.

I thought I had a brain tumor. I thought I had suffered a stroke. Luckily, those diagnoses were ruled out quickly.

36-hours into my visit, the neurologist arrived and said, “I’m getting you out of here. It seems like you have myaesthenia gravis.”

I wore an eye patch for nearly two months and learned that in New York City, no one looks at you twice with an eye patch. I also learned a lot of people have suffered worse – from migraine’s to Bell’s Palsy, cancer and strokes.

Uneven eyes is a symptom of myaesthenia gravis. And man do I look crazy.

It took another month to get the final diagnosis: Myaesthenia gravis, an autoimmune disease.

An excellent neuro-opthalmologist treated me with steroids. After two months, my vision was back to normal.

In retrospect, it feels like it was stress induced (though my doctor wouldn’t agree). I hadn’t been taking care of myself. I was doubting my business. I was overwhelmed by a book I was writing. Two of boys were making major transitions. I thought I was ready. Maybe I wasn’t.

I’m better now and appreciate the importance of good health.

Once the illness ordeal ended, late in June, both Alejandro and Felix graduated. Alejandro graduated from Bard High School Early College. He had been accepted to Cornell and would be going in the fall. Felix graduated from fifth grade and joined his brother, Tomás, at the excellent Math and Science Exploratory (middle) school.

My parents traveled from California, attended the graduations, then we drove to Boston. There, we joined my sister, and her two kids. We boarded the Maasdaam and took a week long cruise along the east coast down the St. Lawrence River to Montreal.

Dinner Time on the Maasdaam

I had never cruised before but it turned out to be a lot of fun. The best thing was the mornings: I’d get up and take a table at one of the restaurants, write in my journal and drink coffee as the ship woke up. Eventually, my father would join me to read the paper. Then little by little our family would arrive.

The only downside was the food. It was excellent but I learned that I had little self-control and by the end of the fifth day, I had chronic heartburn. I’m sure that was due to the over eating.

Karl’s Life messagingLAB

messagingLAB started the year with a two big projects that abruptly came to an end in March. I wasn’t prepared and had to scramble.

Those projects were interesting, pushed me to use digital marketing skills that I hadn’t used in years, as well as coming up with creative marketing solutions for my clients.

Later in the year, two projects required me to draw upon public relations skills that I also hadn’t used in years. One of those projects resulted in some pretty spectacular media placements.

I lost one piece of business because the project ended (we’re still friendly and looking for ways to work together); one piece ended because they ran out of money (we had a great relationship); and one piece of business I lost because the add-on was deemed very expensive.

I lost three proposals because messagingLAB was too expensive. I didn’t like that but took those losses as lessons to work harder to explain the value in hiring me.

I also celebrated five years of working with one client. That was a significant milestone and says a lot about the relationship we have.

I took a bold financial risk# in the middle of the year that didn’t pay off and ended the year at a loss. I’ve been in the hole before and it’s no fun, so I’m taking aggressive steps to move on. (#No, it wasn’t Bitcoin, though I believe an online currency is an inevitability.)

I decided to examine messagingLAB’s offerings. I added media relations and am making it a policy to start all projects with a roadmapping session. I’m also creating a training company to help people understand the opportunities presented by biotechnology.

What’s Your Bio Strategy?

In November, John Cumbers and I published What’s Your Bio Strategy? We interviewed 25 trailblazing academics, entrepeneurs and thought leaders.

It was an incredible experience. And it helped cement me as an author and authority.

I started my career writing music reviews. My first published (and paid!) articles were interviews. I’ve written dozens over the years. The group interviewed for WYBS were among the best.

John invited me to moderate a session at SynBioBeta on Strategy. A month later, I gave a keynote at Biofabricate.

You need a bio strategy.

I’ll admit that in both cases, I was very nervous – it’s been many years since I took the stage – so I practiced. And practiced. And practiced. For SynBioBeta, I spoke to all the people on the panel before we got on stage.

For Biofabricate, I rehearsed and rehearsed and rehearsed. That way, when I got on stage, the presentation was automatic. 

Both were well received.

In December, I taught a bio strategy class to a non-technical audience. They enjoyed it. I also appeared on the FutureTech podcast.

So, I plan to do speaking and teaching in 2018.

The Dragon Burns

When the boys were very young, I would wake up with them, help them go back to sleep. Usually, I couldn’t fall back asleep. So, I picked up the bad habit of surfing infomercials.

Why?

Because infomercials among the most sophisticated marketing stories you can study.

At the time, Alejandro had already started to read chapter books. And like most boys in second, third, fourth grade, he read a lot of books about dragons.

Tomás would continue this and to this day, at age 13, he reads fantasy novels over other genres.

(He also plays Magic the Gathering, which includes a whole story line (Tarkhir) about dragon lords and how all the dragons are extinct. But one guy goes back in time to makes peace among the clans and revive the dragons.)

One night, I had this idea that it would be great to order a dragon from an infomercial.

The idea stuck and I ended up working the idea into a screenplay with a friend. We worked on it for more than a year.

We got busy and dropped the project. But the story never left me. It’s been brewing for five years. During that time, I’ve gotten a lot smarter about what we can create with biology.

I started writing the novel in September and joined a writers group. I workshopped the first 30 pages and got a positive response.

I’m going to continue the book and will tap into my community to get the science right.

It feels like a big book. It’s about applying creativity in new ways.

And now that I’m a bit more than half way through the draft I’m wondering where I’m going to go with it. I’ve written novels and screenplays in the past and wrote them for the enjoyment of it.

That’s how the book feels right now. So, I’m just enjoying the process.

I have no idea what 2018 will hold but I’m excited to define my three words, focus on growing messagingLAB, enjoying the writing, and my family.

2017 started with a sense of dread. 2018 looks to be very exciting.